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Albright

Aging, Immunity, and Infection

Medium: Buch
ISBN: 978-0-89603-644-4
Verlag: Springer Nature Singapore
Erscheinungstermin: 16.06.2003
Lieferfrist: bis zu 10 Tage
The preparation of Aging, Immunity, and Infection has been a "labor of labor. " When we began, there existed a huge literature-but manage­ able, we thought, given our years of experience in the area often referred to as immunogerontology. However, in the time that we have been at work, the new relevant literature has increased at a prodigious rate. The more we read and tried to assimilate, the farther we fell behind. In order to have any hope of completing a book on this rapidly evolving topic, we have been forced to become increasingly selective in covering new and re cent publications. We dare to hope that many read­ ers will find the book useful and only a few will dweIl on the inevitable inadequacies. We consider the book a work in progress, and welcome suggestions for future editions. Five chapters cover several aspects of infection and the decline of immunity with age. The first chapter "Human Aging: Present and Future," is devoted to demographics and theories of senescence. Chap­ ter 2 outlines the gradual breakdown of resistance to infection in the aged individual. Chapters 3 and 4 cover changes in innate and acquired immunity. The final chapter, "Nutrition, Longevity, and Integrity of the Immune System," discusses such provocative ideas as life-span exten­ sion and nutritional intervention for the delay of immunosenescence.

Produkteigenschaften


  • Artikelnummer: 9780896036444
  • Medium: Buch
  • ISBN: 978-0-89603-644-4
  • Verlag: Springer Nature Singapore
  • Erscheinungstermin: 16.06.2003
  • Sprache(n): Englisch
  • Auflage: 2003. Auflage 2003
  • Serie: Infectious Disease
  • Produktform: Gebunden
  • Gewicht: 1170 g
  • Seiten: 242
  • Format (B x H x T): 171 x 235 x 19 mm
  • Ausgabetyp: Kein, Unbekannt

Autoren/Hrsg.

Autoren

Albright, Joseph F

Albright, Julia W

1 Human Aging: Present and Future.- Demographics.- Infectious Diseases of the Aging.- Limits on Life Expectancy and Future Prospects.- Theories of Senescence.- Summary.- References.- 2 Aging and Altered Resistance to Infection.- Relatively Common Bacterial Infections of Aging Humans.- Selected Examples of Age-Associated Susceptibility to Bacterial Infections.- Bacterial Interactions with Mucosal Surfaces.- Antibiotic Resistance and Bacterial Variation.- Viral Infections in Aging Humans.- Protozoan Parasites in Aging Subjects.- Fungal Infections in Aging Subjects.- Summary.- References.- 3 Senescence of Natural/Innate Resistance to Infection.- Pattern Recognizing Receptors of Innate Immunity.- Phagocytic Cells: Monocytes/Macrophages.- Microbial Evasion of Phagocytic Destruction.- Age-Related Changes in Macrophages.- Phagocytic Cells: Neutrophils.- Natural Killer/Lymphokine-Activated Killer Cells.- Summary.- References.- 4 Aging of Adaptive/Acquired Immunity.- Aging of the Thymus and Thymus-Derived (T) Cells.- The Functions and Diversity of Peripheral T Cells.- Summary: Known and Cognizable Effects of Aging T Cells.- Differentiation, Functions, and Aging of B Cells.- Summary.- References.- 5 Nutrition, Longevity, and Integrity of the Immune System.- RCI-Mediated Delay of Immunosenescence.- How Does RCI Promote Life-Span Extension?.- Dietary Restriction vs Malnutrition.- References.- Epilogue.