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Chondrogianni / Pick / Gioran

Proteostasis and Proteolysis

Medium: Buch
ISBN: 978-0-367-49932-7
Verlag: Taylor & Francis Ltd
Erscheinungstermin: 03.12.2021
Lieferfrist: bis zu 10 Tage
Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdown/degradation processes (proteolysis), which are part of a normally functioning proteostatic system: the ubiquitin-proteasome system and autophagy.

Chapter 2 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

Produkteigenschaften


  • Artikelnummer: 9780367499327
  • Medium: Buch
  • ISBN: 978-0-367-49932-7
  • Verlag: Taylor & Francis Ltd
  • Erscheinungstermin: 03.12.2021
  • Sprache(n): Englisch
  • Auflage: 1. Auflage 2021
  • Serie: Oxidative Stress and Disease
  • Produktform: Gebunden
  • Gewicht: 734 g
  • Seiten: 267
  • Format (B x H): 178 x 254 mm
  • Ausgabetyp: Kein, Unbekannt

Autoren/Hrsg.

Herausgeber

Chondrogianni, Niki

Pick, Elah

Gioran, Anna

Preface. Contributors. The Editors. Ribosomal Pauses during Translation and Proteostasis. Protein Folding and Misfolding: Deciphering Mechanisms of Age-Related Diseases. Transcriptional Regulation of Proteostatic Mechanisms. MicroRNAs as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging. mRNA Granules and Proteostasis in Aging and Age-Related Diseases. Phospholipids and the Unfolded Protein Response. Ubiquitin Ligases Involved in Progeroid Syndromes and Age-Associated Pathologies. Role of SUMOylation in Neurodegenerative Diseases and Inflammation. NEDD8 and Oxidative Stress. Structure, Function and Regulators of the 20S Proteasome. Cellular Responses to Proteasome Impairment. Proteasome Fate in Aging and Proteinopathies. The Proteasomal System in Cancer. Proteostasis and Skin Aging. Reactive Oxygen Species and Protein Homeostasis in Skeletal Muscle Regeneration. Protein Degradation in Cardiac Health and Disease. Autophagy in Aging and Oxidative Stress. Autophagy in Aging and Longevity Exemplified by the Aging Heart. Index.