A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.
Produkteigenschaften
- Artikelnummer: 9781617372407
- Medium: Buch
- ISBN: 978-1-61737-240-7
- Verlag: Springer Nature Singapore
- Erscheinungstermin: 09.12.2010
- Sprache(n): Englisch
- Auflage: 1. Auflage. Softcover version of original hardcover Auflage 2006
- Serie: Infectious Disease
- Produktform: Kartoniert, Previously published in hardcover
- Gewicht: 440 g
- Seiten: 284
- Format (B x H x T): 152 x 229 x 17 mm
- Ausgabetyp: Kein, Unbekannt