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Lepenies

Carbohydrate-Based Vaccines

Methods and Protocols

Medium: Buch
ISBN: 978-1-4939-2873-6
Verlag: Springer
Erscheinungstermin: 14.07.2015
Lieferfrist: bis zu 10 Tage
This volume summarizes current cutting-edge methods related to carbohydrate-based vaccines, from the identification of a suitable carbohydrate antigen via the preparation of glycoconjugate vaccines to the characterization of vaccine candidates for their use in pre-clinical and clinical studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Carbohydrate-Based Vaccines: Methods and Protocols aims to be a valuable manual that will facilitate research in the field of carbohydrate-based vaccines.

Produkteigenschaften


  • Artikelnummer: 9781493928736
  • Medium: Buch
  • ISBN: 978-1-4939-2873-6
  • Verlag: Springer
  • Erscheinungstermin: 14.07.2015
  • Sprache(n): Englisch
  • Auflage: 1. Auflage 2015
  • Serie: Methods in Molecular Biology
  • Produktform: Gebunden, HC runder Rücken kaschiert
  • Gewicht: 7117 g
  • Seiten: 255
  • Format (B x H x T): 183 x 260 x 21 mm
  • Ausgabetyp: Kein, Unbekannt

Autoren/Hrsg.

Herausgeber

Lepenies, Bernd

Carbohydrate-based Vaccines: An Overview.- Glycans as Vaccine Antigens and Adjuvants: Immunological Considerations.- The Glycan Array Platform as a Tool to Identify Carbohydrate Antigens.- Antibody-carbohydrate Recognition from Docked Ensembles using the AutoMap Procedure.- Generation of Monoclonal Antibodies against Defined Oligosaccharide Antigens.- Murine Whole-Blood Opsonophagocytosis Assay to Evaluate Protection by Antibodies Raised Against Encapsulated Extracellular Bacteria.- Determination of N-linked Glycosylation in Viral Glycoproteins by Negative Ion Mass Spectrometry and Ion Mobility.- N-Glycosylation Fingerprinting of Viral Glycoproteins by xCGE-LIF.- Temporary Conversion of Protein Amino Groups To Azides: A Synthetic Strategy For Glycoconjugate Vaccines.- Gold Nanoparticles as Carriers For Synthetic Glycoconjugate Vaccines.- Identification and Characterization of Carbohydrate-Based Adjuvants.- Characterization of Carbohydrate Vaccines by NMR Spectroscopy Francesco Berti and Neil Ravenscroft.- Characterisation of Capsular Polysaccharides and Their Glycoconjugates by Hydrodynamic Methods.- Glycoconjugate Vaccines: The Regulatory Framework.