Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
Produkteigenschaften
- Artikelnummer: 9780762305933
- Medium: Buch
- ISBN: 978-0-7623-0593-3
- Verlag: Elsevier Science & Technology
- Erscheinungstermin: 27.12.1999
- Sprache(n): Englisch
- Auflage: Erscheinungsjahr 1999
- Produktform: Gebunden
- Gewicht: 460 g
- Seiten: 200
- Format (B x H): 156 x 234 mm
- Ausgabetyp: Kein, Unbekannt