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Watson / Larson

Immune Dysfunction and Immunotherapy in Heart Disease

Medium: Buch
ISBN: 978-1-4051-5568-7
Verlag: Wiley
Erscheinungstermin: 24.09.2007
Lieferfrist: bis zu 10 Tage
Current heart failure therapeutics affects symptoms without appreciably reducing the mortality rate of 50% in five years -- suggesting a failure in treating the underlying mechanism. This book proposes a new mechanism for heart failure; immune mediated cardiac remodelling for cardiac dysfunction.

The outstanding editor team of two internationally recognized immunologists -- Ronald Watson, who has studied heart disease in immune dysfunction for a decade and has a patent for an immunotherapy of heart disease by immune regulation, and Douglas Larson, whose experience in cardiac transplantation immunology has provided the foundation for research into novel therapeutics for heart failure and hypertension - makes Immune Dysfunction and Immunotherapy in Heart Disease the definitive reference to the state of the science in this area.

The four parts of the book address:

* Immune Dysfunction Leading to Heart Disease: Induction by Physiological Changes

* Immune Dysfunction Promoting CVD: Induction by Transplantation Drugs

* Immune Dysfunction Leading to Heart Dysfunction: Induction or Prevention by Cardiotherapeutic Drugs

* Immune Dysfunction Leading to Heart Disease: Induction by Pathogens

Both researchers and practitioners will find this authoritative volume an excellent source of information on novel immune targeted therapeutics.

Produkteigenschaften


  • Artikelnummer: 9781405155687
  • Medium: Buch
  • ISBN: 978-1-4051-5568-7
  • Verlag: Wiley
  • Erscheinungstermin: 24.09.2007
  • Sprache(n): Englisch
  • Auflage: 1. Auflage 2007
  • Produktform: Gebunden
  • Gewicht: 912 g
  • Seiten: 328
  • Format (B x H x T): 181 x 262 x 21 mm
  • Ausgabetyp: Kein, Unbekannt

Autoren/Hrsg.

Herausgeber

Watson, Ronald Ross

Larson, Douglas F

Larson, Douglas

PART 1: Immune Dysfunction Leading to Heart Disease: Induction by Physiological Changes.

01 Immunosuppression by Ultraviolet Light-B Radiation: a Mediator of Cardiac Remodeling.

02 Immune Mechanisms In Pediatric Cardiovascular Disease.

03 Heart failure - role of autoimmunity.

04 Immune basis of Hypertension in Humans.

05 Immune Dysregulation: Potential Mediator of Metabolic Syndrome-Induced Cardiac Remodeling.

06 T-Helper 2 Cell Cytokines In Remodelling Of Aortic Wall.

07 Effects of TNF-alpha on Cardiac Function.

08 Immunosuppression in Promotion of Cardiac Allograft Vasculopathy.

09 Immunotherapy for left ventricular dysfunction after heart transplantation.

PART 2: Immune Dysfunction Promoting CVD: Induction by Transplantation Drugs.

10 Immunmodulating therapy in chronic heart failure.

11 Statins in Atherosclerosis: Role of Immune Regulation.

12 ACE Inhibitors as Immunmodulators: Treatment of Cardiovascular Disease.

13 Treatment of Heart Failure by Anticytokine Therapies.

PART 3: Immune Dysfunction Leading to Heart Dysfunction: Induction or prevention by Cardiotherapeutic Drugs.

14 Pathogenesis Of Cardiovascular Complications In The Acquired Immunodeficiency Syndrome.

15 Cytokines and T cell-Mediated Responses in Autoimmune Myocarditis.

16 Drugs of abuse: Accentuation of immunomodulation of viral myocarditis.

PART 4: Immune Dysfunction Leading to Heart Disease: Induction by Pathogens.

17 Osteopontin: The link between the Immune System and cardiac remodeling.

18 Inflammatory immune activation in heart failure patients; Therapeutic implications.

19 Role of Innate Immune Dysregulation in Diabetic Heart Failure.

20 Tolerance in Heart Transplantation: Current and Future Role.

21 Neutralization of Th2 cytokines in therapy of cardiovascular pathology.

22 Anti-inflammatory immune therapy in heart disease.

23 Cholesterol Synthesis, Interleukin 6 inflammation and Atherosclerosis - Role of statins, bisphosphonates and plant polyphenols in Atherosclerosis and other diseases of Aging.

24 Autoimmune myocarditis. Treatment with anti-T-cell antibodies.

25 Immunosuppressive Therapy To Counter Cardiac Allograft Vasculopathy.

26 Immunosuppression by Ultraviolet Light-B Radiation: a Mediator of Cardiac Remodeling.

27 Role of oral pathogens in the pathogenesis of coronary heart disease.

28 Myocardial regenerative potential by stem cell transplant.

29 Bioflavanoids and Dietary Anti-Inflammatory Actions: Role in Cardiovascular Diseases